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U.S. Department of Agriculture opens nation’s first biosafety level 4 containment facility for animal disease research

Laboratories

U.S. Department of Agriculture opens nation’s first biosafety level 4 containment facility for animal disease research

Replacing a seven-decade-old animal disease center, the National Bio and Agro-Defense Facility includes the nation’s first facility with biosafety containment capable of housing large livestock.


By Novid Parsi, Contributing Editor | July 10, 2023
U.S. Department of Agriculture opens nation’s first biosafety level 4 containment facility for animal disease research
Photo courtesy U.S. Department of Agriculture

In Manhattan, Kan., the National Bio and Agro-Defense Facility (NBAF), an animal disease research facility, has finished construction. Replacing the 68-year-old Plum Island Animal Disease Center, NBAF, when fully operational, will have labs functioning at multiple biosafety levels—including the nation’s first facility with biosafety level 4 containment capable of housing large livestock.

The 707,000-sf facility has been developed to ensure public health and the safety and security of the nation’s food supply. In 574,000 sf of lab space, scientists will safely study and diagnose high-consequence animal pathogens. In addition, an 87,000-sf utility plant houses boilers, chillers, emergency diesel generators, and other support elements for the main lab facility. 

In addition to its state-of-the-art laboratories, NBAF will have a Biologics Development Module to explore potential vaccines, diagnostic platforms, and veterinary medical countermeasures.

With construction complete, the U.S. Department of Agriculture has begun to assume control of NBAF from the Department of Homeland Security Science and Technology Directorate. This involves confirming laboratory setup and making sure the equipment functions properly. “These are critical initial steps to ensure all research and diagnostics can be accomplished safely and effectively,” Ken Burton, NBAF deputy director, said in a statement.

The preconstruction, construction, and commissioning contract was valued at $1.06 billion. Despite pandemic-related challenges and delays, the project with commissioning came in under the $1.25 billion budget established by federal officials in 2014. 

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